Saturday, 13 July 2013

LEPROSY (Hansen's disease)




Leprosy is a disease that has been in existence even from the biblical times. It is also known as Hansen’s disease (derived from Gerhard A. Hansen, the name of the man who discovered one of the microorganisms responsible for the disease).

Leprosy is an infectious disease caused by the bacteria: Mycobacterium leprae and Mycobacterium lepromatosis

This disease is not that contagious and has a long incubation period (i.e. it takes a long time before the symptoms of the disease starts to manifest) making it hard to know where or when someone caught the disease.

Leprosy occurs worldwide and can be contracted by close, repeated contact with droplets from the nose and mouth of someone with the disease. Children are more vulnerable to the disease than adults. Also, there is evidence that the disease can be transmitted to humans by some animals such as armadillos and even cockroaches.

Leprosy primarily affects the skin, the peripheral nerves (i.e. nerves outside the brain and spinal cord ), mucosa of the upper respiratory tract and even the eyes (excess eye fluid is actually the first most obvious symptom of the disease)

Symptoms of the disease include: runny nose, dry scalp, eye problems, skin lesions, muscle weakness, numbness of fingers and toes, reddish skin, flat nose due to destruction of nasal cartilage etc


                  There are 3 major types of Leprosy:
1.     Tuberculoid: This type is called Paucibacillary leprosy (PL) and is a less severe form of the disease. People with this type of leprosy usually have a few patches of flat, pale-coloured skin. These patches may feel numb because of nerve damage underneath. Tuberculoid leprosy is less contagious than other forms

2.     Lepromatous: This type is called Multibacillary leprosy (ML) and is a more severe form of the disease. It is also more contagious than tuberculod leprosy. It is characterized by wide-spread skin bumps, rashes, lesions, thickened dermis, numbness, muscle weakness. The nose, kidneys, and male reproductive organs may also be affected.

3.     Borderline: This type of leprosy is of intermediate severity, is the most common form, and is a combination of symptoms from the tuberculoid and lepromatous forms

Leprosy can be diagnosed by Skin biopsy. This involves taking a small sample of the skin from a suspicious skin sore and examining it for the presence of Mycobacterium leprae and Mycobacterium lepromatosis

Segregation and quarantining of leper patients (into leper colonies) was, and is still used today in some countries as a means of preventing the spread of the disease. But this method is no longer needed since adequate treatment procedures are now available

This disease can be cured. Examples of drugs used in the treatment of leprosy are dapsone, rifampicin, clofazimine, prednisolone and thalidomide. The BCG vaccine (Bacille Calmette Guerin) can also offer a degree of protection against leprosy.

If untreated, Leprosy can lead to
·        Blindness
·        Disfiguration of the face
·        Shortening of toes and fingers
·        Kidney failure
·        Erectile dysfunction and infertility in men
·        Permanent muscle weakness
·        Permanent damage to the inside of the nose
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